Anti-RIOK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA017866.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA017866.100	100 µl		-		7 - 10 business days*		491.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Involved in the final steps of cytoplasmic maturation of the 40S ribosomal... more

Close menu

Product information "Anti-RIOK1"

Protein function: Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor (PubMed:22072790). The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation (PubMed:21081503). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to rat: 84%

Keywords:	Anti-RIO1, EC=3.6.3.-, Anti-RIO kinase 1, Anti-Serine/threonine-protein kinase RIO1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA017866

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: NVNDFFMRHS VAVMTVRELF EFVTDPSITH ENMDAYLSKA MEIASQRTKE ERSSQDHVDE EVFKRAYIPR TLNEVKNYER DMDIIMKLKE EDMAMNAQQD NILYQTVTGL KKDLSGVQKV PALLENQVEE RTCSDSEDIG SSEC (ATA-APrEST73468)