Anti-RIOK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-457A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-457A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Involved in the final steps of cytoplasmic maturation of the 40S ribosomal... more

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Product information "Anti-RIOK1"

Protein function: Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre- rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor (PubMed:22072790). The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. [The UniProt Consortium]

Keywords:	Anti-RIOK1, EC=3.6.3.-, EC=2.7.11.1, Anti-RIO kinase 1, Anti-Serine/threonine-protein kinase RIO1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-457A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: horse, pig, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, naked mole rat, thirteen-lined ground squirrel, little brown bat, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-457A-T maps to a region between residue 518 and 568 of human RIO kinase 1 using the numbering given in entry NP_113668.2 (GeneID 83732).
Format:	Antigen Affinity Purified