Anti-RIC8A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA041491.25	25 µl		-		3 - 8 business days*		246.00€
ATA-HPA041491.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Guanine nucleotide exchange factor (GEF), which can activate some, but not all,... more

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Product information "Anti-RIC8A"

Protein function: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)- alpha-GDP complex. Also acts as an activator for G(q)- alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 79% and to rat: 77%

Keywords:	Anti-RIC8A, Anti-Synembryn-A, Anti-Protein Ric-8A
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA041491

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TGEEDVIMEA LRSYNQEHSQ SFTFDDAQQE DRKRLAELLV SVLEQGLPPS HRVIWLQSVR ILSRDRNCLD PFTSRQSLQA LACYADISVS EGSVPESADM DVVLES (ATA-APrEST80779)