Anti-Ric-8A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-571A-T	10 µl (10 µg)		-		3 - 7 business days*		165.00€
A304-571A	100 µl (100 µg)		-		3 - 7 business days*		586.00€

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Protein function: Guanine nucleotide exchange factor (GEF), which can activate some, but not all,... more

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Product information "Anti-Ric-8A"

Protein function: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation. [The UniProt Consortium]

Keywords:	Anti-RIC8A, Anti-Synembryn-A, Anti-Protein Ric-8A
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-571A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rhesus monkey, chimpanzee, crab-eating macaque, northern white-cheeked gibbon, small-eared galago)
Immunogen:	synthetic peptide. The epitope recognized by A304-571A-T maps to a region between residue 1 to 50 of human Resistance to Inhibitors of Cholinesterase 8 Homolog A using the numbering given in entry EAW61245.1 (GeneID 60626).
Format:	Antigen Affinity Purified