Anti-Ribosomal S6 Kinase 2

The p90 ribosomal S6 kinases (RSKs) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits. Recent work suggests that RSK2 exerts a tonic regulation on G protein-coupled signaling.Synonyms: RSK2. Immunogen: Peptide from the C-terminal region of rat RSK2. Formulation: (Request formulation change), 100 µl of peptide affinity-purified antibody. Storage Buffer: 10 mM HEPES, pH 7.5, containing 150 nM sodium chloride, 100 µg BSA/ml and 50% glycerol. Host: Rabbit. Applications: WB. Origin: Animal/Rabbit.