Anti-RGS14

Anti-RGS14
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-797A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A303-797A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A303-797A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Regulates G protein-coupled receptor signaling cascades. Inhibits signal... more
Product information "Anti-RGS14"
Protein function: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation, a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Required for the nerve growth factor (NGF)- mediated neurite outgrowth. Involved in stress resistance. May be involved in visual memory processing capacity and hippocampal- based learning and memory. [The UniProt Consortium]
Keywords: Anti-RGS14, Anti-Regulator of G-protein signaling 14
Supplier: Bethyl Laboratories
Supplier-Nr: A303-797A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Rhesus Monkey, Gorilla, Chimpanzee, Crab-eating Macaque, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A303-797A-T maps to a region between residue 516 and 566 of human Regulator of G-Protein Signaling 14 using the numbering given in entry NP_006471.2 (GeneID 10636).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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