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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG45294.50 | 50 µg | - | - |
6 - 14 business days* |
501.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transcription factor required for ciliogenesis and islet cell differentiation... more
Product information "Anti-RFX3"
Protein function: Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes (PubMed:20148032). Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells (PubMed:12411430). [The UniProt Consortium]
| Keywords: | Anti-RFX3, Anti-Regulatory factor X 3, Anti-Regulatory factor X 3, Anti-Transcription factor RFX3, Anti-Transcription factor RFX3 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG45294 |
Properties
| Application: | FC, ICC, IF, IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Recombinant protein containing to human RFX3 |
| MW: | 84 kD |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K09173 | Matching products |
| UniProt ID : | P48380 | Matching products |
| Gene ID : | GeneID 5991 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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