Anti-RFOX1

Anti-RFOX1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES9410.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES9410.100 100 µl - -

10 - 14 business days*

290.00€
 
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates... more
Product information "Anti-RFOX1"
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011], Protein function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Nucleus . Cytoplasm .
Keywords: Anti-A2BP, Anti-RBFOX1, Anti-Fox-1 homolog A, Anti-Ataxin-2-binding protein 1, Anti-RNA binding protein fox-1 homolog 1, Anti-Hexaribonucleotide-binding protein 1, RFOX1 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES9410

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse,
Immunogen: Synthesized peptide derived from human protein . at AA range: 50-130
MW: 43 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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