Anti-Retinol Binding Protein RPB, clone G4E4

1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between amino acids 74-182. The retinol binding protein antibody recognizes reduced and carboxy-methylated RBP as well as the circulatory RBP but not the native form, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). Retinol binding protein is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism. Protein function: Intracellular transport of retinol. [The UniProt Consortium]