Anti-Ret (Ret Proto-oncogene, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, RET51, RET-ELE1)

The recombination of RET tyrosine kinase with several genes, such as GOLGA5 and the H4 gene, results in a consitutively active oncogenic protein. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1000, Western Blot: 1:500, Immunohistochemistry (Paraffin): 10ug/ml , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.