Anti-Renal Cell Carcinoma, clone PN-15

Anti-Renal Cell Carcinoma, clone PN-15
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2939IHC-7ML 7 ml - -

3 - 10 business days

541.00€
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*.... more
Product information "Anti-Renal Cell Carcinoma, clone PN-15"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This mAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation. Protein function: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. [The UniProt Consortium]
Keywords: Anti-CA9, Anti-CAIX, Anti-G250, Anti-pMW1, Anti-CA-IX, Anti-P54/58N, EC=4.2.1.1, Anti-Membrane antigen MN, Anti-Carbonic anhydrase 9, Anti-Carbonic anhydrase IX, Anti-Carbonate dehydratase IX, Anti-RCC-associated antigen G250, Renal Cell Carcinoma Antibod
Supplier: NSJ Bioreagents
Supplier-Nr: V2939IHC-7ML

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: PN-15
Conjugate: No
Host: Mouse
Reactivity: Human, Horse
Immunogen: Microsomal fraction of human renal cortical tissue homogenate
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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