Anti-REDD1

Anti-REDD1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-169A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-169A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-169A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Regulates cell growth, proliferation and survival via inhibition of the... more
Product information "Anti-REDD1"
Protein function: Regulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). Inhibition of mTORC1 is mediated by a pathway that involves DDIT4/REDD1, AKT1, the TSC1-TSC2 complex and the GTPase RHEB. Plays an important role in responses to cellular energy levels and cellular stress, including responses to hypoxia and DNA damage. Regulates p53/TP53-mediated apoptosis in response to DNA damage via its effect on mTORC1 activity. Its role in the response to hypoxia depends on the cell type, it mediates mTORC1 inhibition in fibroblasts and thymocytes, but not in hepatocytes. Required for mTORC1-mediated defense against viral protein synthesis and virus replication. Inhibits neuronal differentiation and neurite outgrowth mediated by NGF via its effect on mTORC1 activity. Required for normal neuron migration during embryonic brain development. Plays a role in neuronal cell death. [The UniProt Consortium]
Keywords: Anti-REDD1, Anti-DDIT4, Anti-REDD-1, Anti-HIF-1 responsive protein RTP801, Anti-DNA damage-inducible transcript 4 protein, Anti-Protein regulated in development and DNA damage response 1
Supplier: Bethyl Laboratories
Supplier-Nr: A302-169A

Properties

Application: WB, IP, ICC/IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse, Rat, Bovine, Dog, Horse, Rabbit, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, African Elephant, Chinese Hamster, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A302-169A-T maps to a region between residue 1 and 50 of human protein regulated in development and DNA damage response 1 (DNA-damage-inducible transcript 4) using the numbering given in entry NP_061931.1 (GeneID 54541).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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