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Anti-Recombinant TRADD, clone C112485

Elabscience
Anti-Recombinant TRADD, clone C112485
NEW
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN302865L.50 50 µl - -

10 - 15 business days*

171.00€
E-AN302865L.100 100 µl - -

10 - 15 business days*

259.00€
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
 
Description Product Citations Certificate of Analysis Reviews 0
Description
Protein function: Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the... more
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Product information "Anti-Recombinant TRADD, clone C112485"
Protein function: Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD (PubMed:23955153, PubMed:7758105, PubMed:8612133). Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (PubMed:7758105, PubMed:8612133). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity) [The UniProt Consortium]
Keywords: Anti-TRADD, Anti-TNFRSF1A-associated via death domain, Anti-Tumor necrosis factor receptor type 1-associated DEATH domain protein, Recombinant TRADD Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN302865L

Properties

Application: WB, IHC, IF, IP, ELISA
Antibody Type: Monoclonal
Clone: C112485
Conjugate: No
Host: Rabbit
Species reactivity: human,mouse,rat
Format: Purified

Database Information

KEGG ID : K03171 | Matching products
UniProt ID : Q15628 | Matching products
Gene ID : GeneID 8717 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Product Citations
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