Anti-Recombinant TPX2, clone A382
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-AN301679L.50 | 50 µl | - |
10 - 15 business days* |
303.00€
|
|||
| E-AN301679L.100 | 100 µl | - |
10 - 15 business days* |
462.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal... more
Product information "Anti-Recombinant TPX2, clone A382"
Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules.Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. TPX2 is inactivated upon binding to importin-alpha .At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation.
| Keywords: | Anti-TPX2, Anti-Protein fls353, Anti-Targeting protein for Xklp2, Anti-Hepatocellular carcinoma-associated antigen 90, Anti-Hepatocellular carcinoma-associated antigen 519, Anti-Restricted expression proliferation-associated protein 100, Anti-Differential |
| Supplier: | Elabscience |
| Supplier-Nr: | E-AN301679L |
Properties
| Application: | IHC, IF, FCM, WB |
| Antibody Type: | Monoclonal |
| Clone: | A382 |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, rat, mouse |
| Immunogen: | Recombinant human TPX2 fragment |
| MW: | 100 kD |
Database Information
| KEGG ID : | K16812 | Matching products |
| UniProt ID : | Q9ULW0 | Matching products |
| Gene ID : | GeneID 22974 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H317 |
| P Phrases: | P261, P272, P280, P302+352, P333+313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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