Anti-Recombinant Smac/Diablo, clone A361
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-AN301658L.50 | 50 µl | - |
7 - 16 business days* |
304.00€
|
|||
| E-AN301658L.100 | 100 µl | - |
7 - 16 business days* |
464.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by... more
Product information "Anti-Recombinant Smac/Diablo, clone A361"
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis-inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance.
| Keywords: | Anti-DIABLO, Anti-Diablo homolog, mitochondrial, Anti-Direct IAP-binding protein with low pI, Anti-Diablo IAP-binding mitochondrial protein, Anti-Second mitochondria-derived activator of caspases, Recombinant Smac/Diablo Monoclonal Antibody |
| Supplier: | Elabscience |
| Supplier-Nr: | E-AN301658L |
Properties
| Application: | WB, IHC, IF, FCM, IP |
| Antibody Type: | Monoclonal |
| Clone: | A361 |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, rat, mouse |
| Immunogen: | Recombinant human Smac/Diablo fragment |
| MW: | 21 kD |
Database Information
| KEGG ID : | K10522 | Matching products |
| UniProt ID : | Q9NR28 | Matching products |
| Gene ID : | GeneID 56616 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H317 |
| P Phrases: | P261, P272, P280, P302+352, P333+313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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