Anti-Recombinant Phospho-IKB alpha (Ser36), clone C133013

Anti-Recombinant Phospho-IKB alpha (Ser36), clone C133013
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN303393L.50 50 µl - -

10 - 15 business days*

171.00€
E-AN303393L.100 100 µl - -

10 - 15 business days*

259.00€
 
Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL... more
Product information "Anti-Recombinant Phospho-IKB alpha (Ser36), clone C133013"
Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals (PubMed:1493333, PubMed:36651806, PubMed:7479976). On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription (PubMed:7479976, PubMed:7628694, PubMed:7796813, PubMed:7878466) [The UniProt Consortium]
Keywords: Anti-NFKBIA, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha, Anti-Major histocompatibility complex enhancer-binding protein MAD3, Recombinant Phospho-IKB alpha (Ser36) Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN303393L

Properties

Application: WB, FCM
Antibody Type: Monoclonal
Clone: C133013
Conjugate: No
Host: Rabbit
Species reactivity: human,mouse,rat
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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