Anti-Recombinant ITGB6, clone C132874

Anti-Recombinant ITGB6, clone C132874
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN303254L.50 50 µl - -

10 - 15 business days*

171.00€
E-AN303254L.100 100 µl - -

10 - 15 business days*

259.00€
 
Protein function: Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and... more
Product information "Anti-Recombinant ITGB6, clone C132874"
Protein function: Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (PubMed:17158881, PubMed:17545607). It recognizes the sequence R-G-D in its ligands (PubMed:17158881, PubMed:17545607). Internalization of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion (PubMed:17158881, PubMed:17545607). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:17158881). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:15184403, PubMed:22278742, PubMed:28117447) (Microbial infection) Integrin ITGAV:ITGB6 acts as a receptor for Coxsackievirus A9 and Coxsackievirus B1 (Microbial infection) Integrin ITGAV:ITGB6 acts as a receptor for Herpes simplex virus-1/HHV-1 (PubMed:24367260) [The UniProt Consortium]
Keywords: Anti-ITGB6, Anti-Integrin beta-6, Recombinant ITGB6 Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN303254L

Properties

Application: WB
Antibody Type: Monoclonal
Clone: C132874
Conjugate: No
Host: Rabbit
Species reactivity: human,mouse,rat
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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