Anti-Recombinant Ikaros, clone C111862

Anti-Recombinant Ikaros, clone C111862
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN302242L.50 50 µl - -

10 - 15 business days*

171.00€
E-AN302242L.100 100 µl - -

10 - 15 business days*

259.00€
 
Protein function: Transcription regulator of hematopoietic cell differentiation... more
Product information "Anti-Recombinant Ikaros, clone C111862"
Protein function: Transcription regulator of hematopoietic cell differentiation (PubMed:17934067). Binds gamma-satellite DNA (PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed:17135265, PubMed:17934067) [The UniProt Consortium]
Keywords: Anti-IKZF1, Anti-DNA-binding protein Ikaros, Anti-Lymphoid transcription factor LyF-1, Anti-Ikaros family zinc finger protein 1, Recombinant Ikaros Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN302242L

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Monoclonal
Clone: C111862
Conjugate: No
Host: Rabbit
Species reactivity: human,mouse,rat
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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