Anti-Recombinant GRK2, clone A240

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN301541L.50 50 µl -

7 - 16 business days*

304.00€
E-AN301541L.100 100 µl -

7 - 16 business days*

464.00€
 
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related... more
Product information "Anti-Recombinant GRK2, clone A240"
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity. Inhibits relaxation of airway smooth muscle in response to blue light.
Keywords: Anti-GRK2, Anti-Beta-adrenergic receptor kinase 1, Anti-G-protein coupled receptor kinase 2, Recombinant GRK2 Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN301541L

Properties

Application: WB, IF
Antibody Type: Monoclonal
Clone: A240
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse
Immunogen: Recombinant human GRK2 fragment
MW: 80 kD

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317
P Phrases: P261, P272, P280, P302+352, P333+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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