Anti-Recombinant CENP-A, clone A184

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN301489L.50 50 µl -

10 - 15 business days*

303.00€
E-AN301489L.100 100 µl -

10 - 15 business days*

462.00€
 
Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes.... more
Product information "Anti-Recombinant CENP-A, clone A184"
Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore .The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3.May serve as an epigenetic mark that propagates centromere identity through replication and cell division.Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis.
Keywords: Anti-CENPA, Anti-Centromere protein A, Anti-Centromere autoantigen A, Anti-Histone H3-like centromeric protein A, Recombinant CENP-A Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN301489L

Properties

Application: WB, IHC, IF, FCM
Antibody Type: Monoclonal
Clone: A184
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse
Immunogen: Recombinant human CENP-A fragment
MW: 18 kD

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317
P Phrases: P261, P272, P280, P302+352, P333+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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