Anti-Recombinant Cdc25C, clone A595

Anti-Recombinant Cdc25C, clone A595
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN301883L.50 50 µl -

7 - 16 business days*

304.00€
E-AN301883L.100 100 µl -

7 - 16 business days*

464.00€
 
Cdc25C is a protein phosphatase responsible for dephosphorylating and activating cdc2, a crucial... more
Product information "Anti-Recombinant Cdc25C, clone A595"
Cdc25C is a protein phosphatase responsible for dephosphorylating and activating cdc2, a crucial step in regulating the entry of all eukaryotic cells into mitosis. Cdc25C is constitutively phosphorylated at Ser216 throughout interphase by c-TAK1, while phosphorylation at this site is DNA damage-dependent at the G2/M checkpoint. When phosphorylated at Ser216, Cdc25C binds to members of the 14-3-3 family of proteins, sequestering Cdc25C in the cytoplasm and thereby preventing premature mitosis. The checkpoint kinases Chk1 and Chk2 phosphorylate Cdc25C at Ser216 in response to DNA damage.
Keywords: Anti-CDC25C, Anti-M-phase inducer phosphatase 3, Anti-Dual specificity phosphatase Cdc25C, Recombinant Cdc25C Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN301883L

Properties

Application: WB
Antibody Type: Monoclonal
Clone: A595
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse
Immunogen: Recombinant human Cdc25C fragment
MW: 53 kD

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317
P Phrases: P261, P272, P280, P302+352, P333+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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