Anti-Recombinant CBX4, clone A527

Anti-Recombinant CBX4, clone A527
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN301815L.50 50 µl -

10 - 15 business days*

303.00€
E-AN301815L.100 100 µl -

10 - 15 business days*

462.00€
 
CBX4 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3... more
Product information "Anti-Recombinant CBX4, clone A527"
CBX4 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. CBX4 itself is a SUMO E3 ligase, and its function influences EMT, DNA damage response, tumor angiogenesis, and self-renewal. E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. It is involved in the SUMOylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression.
Keywords: Anti-CBX4, Anti-Polycomb 2 homolog, Anti-Chromobox protein homolog 4, Anti-E3 SUMO-protein ligase CBX4, Recombinant CBX4 Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN301815L

Properties

Application: WB, IHC
Antibody Type: Monoclonal
Clone: A527
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse
Immunogen: Recombinant human CBX4 fragment
MW: 61 kD

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317
P Phrases: P261, P272, P280, P302+352, P333+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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