Anti-Recombinant BUB3, clone C112684

Anti-Recombinant BUB3, clone C112684
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN303064L.50 50 µl - -

10 - 15 business days*

171.00€
E-AN303064L.100 100 µl - -

10 - 15 business days*

259.00€
 
Protein function: Has a dual function in spindle-assembly checkpoint signaling and in promoting... more
Product information "Anti-Recombinant BUB3, clone C112684"
Protein function: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1 [The UniProt Consortium]
Keywords: Anti-BUB3, Anti-Mitotic checkpoint protein BUB3, Recombinant BUB3 Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN303064L

Properties

Application: WB, IHC, ICC/IF
Antibody Type: Monoclonal
Clone: C112684
Conjugate: No
Host: Rabbit
Species reactivity: human,mouse,rat
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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