Anti-Recombinant ATP Citrate Lyase, clone A772

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN302052L.50 50 µl -

7 - 16 business days*

304.00€
E-AN302052L.100 100 µl -

7 - 16 business days*

464.00€
 
ATP-citrate lyase (ACL) is a homotetramer that catalyzes the formation of acetyl-CoA and... more
Product information "Anti-Recombinant ATP Citrate Lyase, clone A772"
ATP-citrate lyase (ACL) is a homotetramer that catalyzes the formation of acetyl-CoA and oxaloacetate (OAA) in the cytosol, which is the keystep for the biosynthesis of fatty acids, cholesterol and acetylcholine, as well as for glucogenesis. Nutrients and hormones regulate theexpression level and phosphorylation of ATP-citrate lyase. It is phosphorylated by GSK-3 on Thr446 and Ser450. Ser455 of ATP-citrate lyasehas been reported to be phosphorylated by PKA and Akt. Phosphorylation on Ser455 abolishes the homotropic allosteric regulation by citrateand enhances the catalytic activity of the enzyme.
Keywords: Anti-ACLY, Anti-ATP-citrate synthase, Anti-Citrate cleavage enzyme, Anti-ATP-citrate (pro-S-)-lyase, Recombinant ATP Citrate Lyase Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN302052L

Properties

Application: WB, IHC
Antibody Type: Monoclonal
Clone: A772
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse
Immunogen: Peptide. This information is proprietary to PTMab.
MW: 125 kD

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317
P Phrases: P261, P272, P280, P302+352, P333+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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