Anti-Recombinant Arp3, clone C111951

Anti-Recombinant Arp3, clone C111951
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN302331L.50 50 µl - -

10 - 15 business days*

171.00€
E-AN302331L.100 100 µl - -

10 - 15 business days*

259.00€
 
Protein function: ATP-binding component of the Arp2/3 complex, a multiprotein complex that... more
Product information "Anti-Recombinant Arp3, clone C111951"
Protein function: ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9000076). Seems to contact the pointed end of the daughter actin filament (PubMed:9000076). In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation (PubMed:29058690). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947). Plays a role in ciliogenesis (PubMed:20393563) [The UniProt Consortium]
Keywords: Anti-ACTR3, Anti-Actin-like protein 3, Anti-Actin-related protein 3, Recombinant Arp3 Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN302331L

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Monoclonal
Clone: C111951
Conjugate: No
Host: Rabbit
Species reactivity: human,mouse,rat
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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