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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG42831.50 | 50 µg | - | - |
6 - 14 business days* |
551.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Key regulator of entry into cell division (PubMed:17671431). Directly involved... more
Product information "Anti-RBL1 / p107"
Protein function: Key regulator of entry into cell division (PubMed:17671431). Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation (PubMed:8319904). May act as a tumor suppressor (PubMed:8319904). {ECO:0000250, UniProtKB:Q64701, ECO:0000269, PubMed:17671431, ECO:0000269, PubMed:8319904}. [The UniProt Consortium]
| Keywords: | Anti-RBL1, Anti-p107, Anti-pRb1, Anti-p107, Anti-pRb1, Anti-Retinoblastoma-like protein 1, Anti-Retinoblastoma-like protein 1, Anti-107 kDa retinoblastoma-associated protein, Anti-107 kDa retinoblastoma-associated protein |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG42831 |
Properties
| Application: | IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, rat (Expected: mouse, hamster) |
| Immunogen: | Synthetic peptide corresponding to aa. 1048-1068 of Human RBL1 / p107. (QENDDVLLKRLQDVVSERANH) |
| MW: | 121 kD |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K04681 | Matching products |
| UniProt ID : | P28749 | Matching products |
| Gene ID : | GeneID 5933 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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