Anti-QKI

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA019123.25	25 µl		-		3 - 8 business days*		330.00€
ATA-HPA019123.100	100 µl		-		3 - 8 business days*		463.00€

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Protein function: RNA-binding protein that plays a central role in myelinization... more

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Product information "Anti-QKI"

Protein function: RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY- 3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-QKI, Anti-HKQ, Anti-Hqk, Anti-HqkI, Anti-Protein quaking
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA019123

Properties

Application:	ICC, IHC, WB, ChIP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RAEIKLKRAV EEVKKLLVPA AEGEDSLKKM QLMELAILNG TYRDANIKSP ALAFSLAATA QAAPRIITGP APVLPPAALR TPTPAGPTIM PLIRQIQTAV MPNGTPHPTA AIVPPGPEAG LIYTPYEYPY TLAPATSILE YPIEPSGVL (ATA-APrEST86699)