Anti-PUS7

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA024116.25	25 µl		-		3 - 8 business days*		330.00€
ATA-HPA024116.100	100 µl		-		3 - 8 business days*		463.00€

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Protein function: Pseudouridylate synthase that catalyzes pseudouridylation of RNAs... more

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Product information "Anti-PUS7"

Protein function: Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141, PubMed:30778726). Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141). Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919). In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types (PubMed:29628141). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 95%

Keywords:	Anti-Pseudouridylate synthase 7 homolog
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA024116

Properties

Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PGFDVIYPKH KIQEAYREML TADNLDIDNM RHKIRDYSLS GAYRKIIIRP QNVSWEVVAY DDPKIPLFNT DVDNLEGKTP PVFASEGKYR ALKMDFSLPP STYATMAIRE VLKMDTSIKN QTQ (ATA-APrEST74873)