Anti-PSMD10

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA002920.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA002920.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Acts as a chaperone during the assembly of the 26S proteasome, specifically of... more

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Product information "Anti-PSMD10"

Protein function: Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 85%

Keywords:	Anti-PSMD10, Anti-Gankyrin, Anti-p28(GANK), Anti-26S proteasome regulatory subunit p28, Anti-26S proteasome non-ATPase regulatory subunit 10
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA002920

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EGCVSNLMVC NLAYSGKLEE LKESILADKS LATRTDQDSR TALHWACSAG HTEIVEFLLQ LGVPVNDKDD AGWSPLHIAA SAGRDEIVKA LLGKGAQVNA VNQNGCTPL (ATA-APrEST74349)