Anti-Prolactin Receptor, clone B6.2

Anti-Prolactin Receptor, clone B6.2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3171IHC-7ML 7 ml - -

3 - 10 business days*

752.00€
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. It... more
Product information "Anti-Prolactin Receptor, clone B6.2"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription. Protein function: This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. [The UniProt Consortium]
Keywords: Anti-PRLR, Anti-PRL-R, Anti-Prolactin receptor, Prolactin Receptor Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3171IHC

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: B6.2
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Semi-purified human prolactin receptor was used as the immunogen for this Prolactin Receptor antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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