Anti-PRKG2

Anti-PRKG2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB18575.20 20 µl -

9 - 20 business days*

149.00€
 
Protein function: Crucial regulator of intestinal secretion and bone growth. Phosphorylates and... more
Product information "Anti-PRKG2"
Protein function: Crucial regulator of intestinal secretion and bone growth. Phosphorylates and activates CFTR on the plasma membrane. Plays a key role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum. Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity. Phosphorylates GRIA1/GLUR1 at Ser-863. Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2 in mechanically stimulated osteoblasts. Under fluid shear stress, mediates ERK activation and subsequent induction of FOS, FOSL1/FRA1, FOSL2/FRA2 and FOSB that play a key role in the osteoblast anabolic response to mechanical stimulation. [The UniProt Consortium]
Keywords: Anti-cGK2, Anti-PRKG2, Anti-cGKII, Anti-cGK 2, Anti-PRKGR2, EC=2.7.11.12, Anti-cGMP-dependent protein kinase 2, Anti-cGMP-dependent protein kinase II
Supplier: Assay Genie
Supplier-Nr: CAB18575

Properties

Application: WB, IF, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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