Anti-Presenilin-2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-342A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A304-342A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Probable catalytic subunit of the gamma-secretase complex, an endoprotease... more

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Product information "Anti-Presenilin-2"

Protein function: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins. [The UniProt Consortium]

Keywords:	Anti-AD4, Anti-PSEN2, EC=3.4.23.-
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-342A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat, bovine, pig, orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A304-342A-T maps to a region between residue 275 to 325 of human Presenilin 2 using the numbering given in entry NP_000438.2 (GeneID 5664).
Format:	Antigen Affinity Purified