Anti-PRC1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41360.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Key regulator of cytokinesis that cross-links antiparrallel microtubules at an... more

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Product information "Anti-PRC1"

Protein function: Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). [The UniProt Consortium]

Keywords:	Anti-Protein regulator of cytokinesis 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41360

Properties

Application:	FC, IHC (paraffin), IP, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide derived from Human PRC1
MW:	72 kD
Format:	Affinity Purified