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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA039837.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
| ATA-HPA039837.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May... more
Product information "Anti-PPP4R2"
Protein function: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 95%
| Keywords: | Anti-PPP4R2, Anti-SBBI57, Anti-Serine/threonine-protein phosphatase 4 regulatory subunit 2 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA039837 |
Properties
| Application: | ICC, IHC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: FTIQRLCELL TDPRRNYTGT DKFLRGVEKN VMVVSCVYPS SEKNNSNSLN RMNGVMFPGN SPSYTERSNI NGPGTPRPLN RPKVSLSAPM TTNGLPESTD (ATA-APrEST87342) |
Database Information
| KEGG ID : | K15425 | Matching products |
| UniProt ID : | Q9NY27 | Matching products |
| Gene ID | GeneID 151987 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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