Anti-PPP1CC

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-16728.20 20 µl -

7 - 16 business days*

71.00€
E-AB-16728.60 60 µl -

7 - 16 business days*

143.00€
E-AB-16728.120 120 µl -

7 - 16 business days*

238.00€
E-AB-16728.200 200 µl -

7 - 16 business days*

396.00€
 
The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is... more
Product information "Anti-PPP1CC"
The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Protein function: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T- cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). [The UniProt Consortium]
Keywords: Anti-PP-1G, Anti-PPP1CC, EC=3.1.3.16, Anti-Protein phosphatase 1C catalytic subunit, Anti-Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PPP1CC Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-16728

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide of human PPP1CC
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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