Anti-PPM1D

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA022277.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA022277.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Involved in the negative regulation of p53 expression (PubMed:23242139).... more

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Product information "Anti-PPM1D"

Protein function: Involved in the negative regulation of p53 expression (PubMed:23242139). Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins (PubMed:15870257, PubMed:16311512). Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629). Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 97%

Keywords:	Anti-WIP1, Anti-PPM1D, Anti-PP2C-delta, EC=3.1.3.16, Anti-Protein phosphatase 1D, Anti-p53-induced protein phosphatase 1, Anti-Protein phosphatase 2C isoform delta, Anti-Protein phosphatase magnesium-dependent 1 delta
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA022277

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KHKYIILGSD GLWNMIPPQD AISMCQDQEE KKYLMGEHGQ SCAKMLVNRA LGRWRQRMLR ADNTSAIVIC ISPEVDNQGN FTNEDELYLN LT (ATA-APrEST75166)