Anti-Potassium Chloride Cotransporter / KCC2

Anti-Potassium Chloride Cotransporter / KCC2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG56210.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is... more

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Product information "Anti-Potassium Chloride Cotransporter / KCC2"

Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition. Involved in the regulation of dendritic spine formation and maturation (PubMed:24668262). [The UniProt Consortium]

Keywords:	Anti-KCC2, Anti-hKCC2, Anti-SLC12A5, Anti-K-Cl cotransporter 2, Anti-Neuronal K-Cl cotransporter, Anti-Solute carrier family 12 member 5, Anti-Electroneutral potassium-chloride cotransporter 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56210

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	KLH-conjugated synthetic peptide around aa. 5-33 (N-terminus) of Human KCC2
MW:	126 kD
Format:	Purified