Anti-PON2

Anti-PON2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32234 100 µg - -

3 - 10 business days

503.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. PON2 is an enzyme that in humans is... more
Product information "Anti-PON2"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. PON2 is an enzyme that in humans is encoded by the PON2 gene. It is mapped to 7q21.3. This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones and important bacterial quorum-sensing mediators suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Protein function: Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. [The UniProt Consortium]
Keywords: Anti-PON2, Anti-PON 2, EC=3.1.1.2, EC=3.1.1.81, Anti-A-esterase 2, Anti-Aromatic esterase 2, Anti-Serum aryldialkylphosphatase 2, Anti-Serum paraoxonase/arylesterase 2, PON2 Antibody
Supplier-Nr: R32234

Properties

Application: WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Immunogen: Amino acids AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSID of human PON2 were used as the immunogen for the PON2 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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