Anti-POMC / ACTH, clone ADEC-16

Anti-POMC / ACTH, clone ADEC-16
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ4873 100 µl - -

3 - 10 business days*

755.00€
 
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. This gene encodes a... more
Product information "Anti-POMC / ACTH, clone ADEC-16"
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [RefSeq] Protein function: [Corticotropin]: Stimulates the adrenal glands to release cortisol. [The UniProt Consortium]
Keywords: Anti-POMC, POMC Antibody / ACTH
Supplier: NSJ Bioreagents
Supplier-Nr: RQ4873

Properties

Application: WB
Antibody Type: Monoclonal
Clone: ADEC-16
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: A synthetic peptide specific to human POMC
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-POMC / ACTH, clone ADEC-16"
Write a review
or to review a product.
Viewed