Anti-POLRMT

Anti-POLRMT
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA067428.100 100 µl

7 - 10 business days*

491.00€
 
Rabbit Polyclonal POLRMT Antibody against Human RNA polymerase mitochondrial. Validated for... more
Product information "Anti-POLRMT"
Rabbit Polyclonal POLRMT Antibody against Human RNA polymerase mitochondrial. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000020329: 79%, ENSRNOG00000024879: 80%. Protein function: DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates (PubMed:21278163). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA (PubMed:29149603). In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand (PubMed:29149603). [The UniProt Consortium]
Keywords: Anti-MtRPOL, EC=2.7.7.6, Anti-DNA-directed RNA polymerase, mitochondrial
Supplier: Atlas Antibodies
Supplier-Nr: HPA067428

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: LDSKVKQIGG GIQSITYTHN GDISRKPNTR KQKNGFPPNF IHSLDSSHMM LTALHCYRKG LTFVSVHDCY WTHAADVSVM NQVCREQFVR
Format: Affinity Purified

Handling & Safety

Storage: -20°C (+4 °C for short term storage)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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