Anti-POLRMT

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA006366.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA006366.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA... more

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Product information "Anti-POLRMT"

Protein function: DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates (PubMed:21278163). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA (PubMed:29149603). In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand (PubMed:29149603). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 68% and to rat: 65%

Keywords:	Anti-MtRPOL, EC=2.7.7.6, Anti-DNA-directed RNA polymerase, mitochondrial
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA006366

Properties

Application:	IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ELVYVLFMVK DAGLTPDLLS YAAALQCMGR QDQDAGTIER CLEQMSQEGL KLQALFTAVL LSEEDRATVL KAVHKVKPTF SLPPQLPPPV NTSKLLRDVY AKDGRVSYPK LHLPLKTLQC LFEKQLH (ATA-APrEST86643)