Anti-POLR3D (IHC)

Anti-POLR3D (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00662-T 10 µl (5+ slides) -

3 - 9 business days

125.00€
IHC-00662 100 µl (50+ slides) -

3 - 9 business days

456.00€
 
Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using... more
Product information "Anti-POLR3D (IHC)"
Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. [The UniProt Consortium]
Keywords: Anti-BN51, Anti-POLR3D, Anti-Protein BN51, Anti-RPC53 homolog, Anti-RNA polymerase III subunit C4, Anti-RNA polymerase III 47 kDa subunit, Anti-DNA-directed RNA polymerase III subunit D, Anti-DNA-directed RNA polymerase III subunit RPC4
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00662-T

Properties

Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human (Expected: Gorilla, Chimpanzee)
Immunogen: The epitope recognized by IHC-00662 maps to a region between residue 175 and 225 of human DNA-directed RNA polymerase III subunit D using the numbering given in entry NP_001713.2 (GeneID 661).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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