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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA027516.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
ATA-HPA027516.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using... more
Product information "Anti-POLR3C"
Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. Preferentially binds single-stranded DNA (ssDNA) in a sequence-independent manner (PubMed:21358628). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 95%
Keywords: | Anti-RPC62, Anti-POLR3C, Anti-RNA polymerase III subunit C3, Anti-RNA polymerase III 62 kDa subunit, Anti-DNA-directed RNA polymerase III subunit C, Anti-DNA-directed RNA polymerase III subunit RPC3 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA027516 |
Properties
Application: | ICC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VINLHKALAS LATATLESVV QERFGSRCAR IFRLVLQKKH IEQKQVEDFA MIPAKEAKDM LYKMLSENFM SLQEIPKTPD HAPSRTFYLY TVNILSAARM (ATA-APrEST77148) |
Database Information
KEGG ID : | K03023 | Matching products |
UniProt ID : | Q9BUI4 | Matching products |
Gene ID | GeneID 10623 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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