Anti-POLR2M

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA068141.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA068141.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Isoform 1 appears to be a stable component of the Pol II(G) complex form of RNA... more

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Product information "Anti-POLR2M"

Protein function: Isoform 1 appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II). Pol II synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNA polymerase II transcription machinery. Isoform 1 may play a role in the Mediator complex-dependent regulation of transcription activation. Isoform 1 acts in vitro as a negative regulator of transcriptional activation, this repression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a level equivalent to that of Pol II. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 67% and to rat: 70%

Keywords:	Anti-POLR2M, Anti-GRINL1A, Anti-Glutamate receptor-like protein 1A, Anti-DNA-directed RNA polymerase II subunit M, Anti-DNA-directed RNA polymerase II subunit GRINL1A
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA068141

Properties

Application:	ICC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SSQAEDTSSS FDNLFIDRLQ RITIADQGEQ QSEENASTKN LTGLSSGTEK KPHYMEVLEM RAK (ATA-APrEST90234)