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Product information "Anti-POLE3 / CHRAC17, clone PCRP-POLE3-3D3"
Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Nucleus. Positive Control: HeLa or K562 cells. Chromosome Location: 9q32. Protein Function: Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity). Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 (PubMed:10801849). Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex (PubMed:14759371) [The Uniprot Consortium]
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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