Anti-Podoplanin (Clone pmab-1)

Anti-Podoplanin (Clone pmab-1)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay11005-1 1 each -

1 - 10 business days

269.00€
 
Podoplanin is a 43 kD type 1 transmembrane glycoprotein found on many tissues. Podoplanin appears... more
Product information "Anti-Podoplanin (Clone pmab-1)"
Podoplanin is a 43 kD type 1 transmembrane glycoprotein found on many tissues. Podoplanin appears to be differentially expressed by lymphatic endothelial cells but not blood vessel endothelial cells. Podoplanin has also been found to be expressed on a wide variety of tumors. It appears to be involved in lymphangioigenesis and promoting cell migration. Recently, there are indications of podoplanin presence on Th17 cells. In a murine EAE model for autoimmune disease it has been shown that Th17 cells migrate quickly to the CNS at EAE onset. Injection of antibody to podoplanin in mice also immunized with myelin antigen to induce EAE results in elevated numbers of Th17 cells in the CNS. Thus as in effecting migration of tumor cells, podoplanin may also promote migration of committed Th17 cells to sites of inflammation in autoimmune diseases.
Keywords: Anti-T1A, Anti-Gp38, Anti-Pdpn, Anti-OTS-8, Anti-Aggrus, Anti-T1-alpha, Anti-Podoplanin, Anti-PA2.26 antigen, Anti-Glycoprotein 38, Anti-Transmembrane glycoprotein E11
Supplier: Cayman Chemical
Supplier-Nr: 11005-1

Properties

Application: FC, WB
Antibody Type: Monoclonal
Clone: pmab-1
Host: Rat
Reactivity: Mouse
Immunogen: Mouse Podoplanin
Format: Purified

Database Information

KEGG ID : K16778 | Search using KEGG ID
UniProt ID : Q62011 | Search using UniProt ID

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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