Anti-PLXNB2

Anti-PLXNB2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA003100.25 25 µl -

7 - 10 business days*

246.00€
ATA-HPA003100.100 100 µl -

7 - 10 business days*

491.00€
 
Protein function: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important... more
Product information "Anti-PLXNB2"
Protein function: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A- mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12183458). Plays a role in axon guidance, invasive growth and cell migration (PubMed:15184888). May modulate the activity of RAC1 and CDC42. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: Anti-MM1, Anti-PLXNB2, Anti-KIAA0315, Anti-Plexin-B2
Supplier: Atlas Antibodies
Supplier-Nr: HPA003100

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DSPSNKLLYA KEISTYKKMV EDYYKGIRQM VQVSDQDMNT HLAEISRAHT DSLNTLVALH QLYQYTQKYY DEIINALEED PAAQKMQLAF RLQQIAAALE NKVTD (ATA-APrEST73598)

Database Information

KEGG ID : K06821 | Matching products
UniProt ID : O15031 | Matching products
Gene ID : GeneID 23654 | Matching products
Protein Atlas Nr. : ENSG00000196576

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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