Anti-PLGF, clone PLGF94

Anti-PLGF, clone PLGF94
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2223-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V2223-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The onset of angiogenesis is... more
Product information "Anti-PLGF, clone PLGF94"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast-, platelet derived-, vascular endothelial- and placenta- growth factor (PLGF). Like vascular endothelial growth factor, several PLGF variants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PLGF signaling. While VEGF homodimers and VEGF/PLGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PLGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PLGF. VEGF and PLGF share a common receptor, Flt-1, and may also activate Flk-1/KDR. Protein function: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. [The UniProt Consortium]
Keywords: Anti-PGF, Anti-PlGF, Anti-PGFL, Anti-Placenta growth factor, PLGF Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2223

Properties

Application: ELISA, FA (testing)
Antibody Type: Monoclonal
Clone: PLGF94
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant human PLGF protein was used as the immunogen for this antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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