Anti-Plexin-A3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-473A-T	10 µl (10 µg)		-		2 - 8 business days*		165.00€
A304-473A	100 µl (100 µg)		-		2 - 8 business days*		586.00€

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Protein function: Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3... more

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Product information "Anti-Plexin-A3"

Protein function: Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [The UniProt Consortium]

Keywords:	Anti-PLXN4, Anti-PLXNA3, Anti-Plexin-4, Anti-Plexin-A3, Anti-Semaphorin receptor SEX
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-473A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rabbit, orangutan, gorilla, chimpanzee, white-tufted-ear marmoset, dusky titi monkey, northern white-cheeked gibbon, small-eared galago, chinese tree shrew)
Immunogen:	synthetic peptide. The epitope recognized by A304-473A-T maps to a region between residue 1050 to 1100 of human Plexin-A3 using the numbering given in entry NP_059984.2 (GeneID 55558).
Format:	Antigen Affinity Purified