Anti-PlexB

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1: 64,000 confirmed by ELISA, 3. WB positive with the immunogen protein (not applicable for synthetic peptide). Applications: ELISA, WB (positive for the recombinant immunogen protein/peptide). Buffer: Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Protein function: Transmembrane receptor that binds the molecular guidance cue Sema2a, to regulate axon guidance and possibly salivary gland positioning in embryos (PubMed:11604137, PubMed:16672342). Acts as a receptor for Sema2a and seems to transduce signal by suppressing Rac activity and enhancing Rho activity (PubMed:11604137, PubMed:16672342). As transmembrane receptor for Sema2a, involved in peripheral and central nervous system axon guidance (PubMed:11604137, PubMed:16672342, PubMed:27618755). Function in neurons is essential for adult survival, motor neuron survival, and is important for climbing behavior and activity (PubMed:37041188). During embryogenesis, plays an important role in correct salivary gland positioning (PubMed:27618755). [The UniProt Consortium]